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RAI16 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86V87 |
|---|---|
| Clone Names | 2081905 |
| Gene ID | 64760 |
|---|---|
| Other Names | Protein FAM160B2, Retinoic acid-induced protein 16, FAM160B2, RAI16 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6235a was selected from the C-term region of human RAI16 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | FHIP2B (HGNC:16492) |
|---|---|
| Function | Able to activate MAPK/ERK and TGFB signaling pathways (PubMed:22971576). May regulate the activity of genes involved in intestinal barrier function and immunoprotective inflammation (By similarity). May play a role in cell proliferation (PubMed:22971576). |
| Tissue Location | Expressed in liver.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Retinoic acid plays a critical role in development, cellular growth, and differentiation and induces the expression of a variety of genes. RAI16 expression is induced by retinoic acid; its precise cellular function remains to be determined.
References
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
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