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M Sirt3 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8R104
Other Accession NP_071878.2
Peptide ID 44179
Additional Information
Gene ID 64384
Other Names NAD-dependent protein deacetylase sirtuin-3, 351-, Regulatory protein SIR2 homolog 3, SIR2-like protein 3, mSIR2L3, Sirt3, Sir2l3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Sirt3
Synonyms Sir2l3
Function NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Cellular Location Isoform L: Mitochondrion matrix.
Tissue Location Strongly expressed in liver and kidney. Weakly expressed in lung.
Research Areas
Citations (0)

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SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.


Hirschey, M.D., et al. Nature 464(7285):121-125(2010)Pillai, V.B., et al. J. Biol. Chem. 285(5):3133-3144(2010)Kim, H.S., et al. Cancer Cell 17(1):41-52(2010)

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$ 80.00
Cat# BP6242b
(40 western blots)
Availability: In Stock
Bulk Size
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