|Other Names||Protein Tob2, Protein Tob4, Transducer of erbB-2 2, TOB2, KIAA1663, TOB4, TROB2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6274a was selected from the N-term region of human TOB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1663, TOB4, TROB2|
|Function||Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases.|
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Provided below are standard protocols that you may find useful for product applications.
TOB2 belongs to the TOB /BTG1 family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.
Sasajima,H., Eur. J. Biochem. 269 (14), 3596-3604 (2002)Yoshida,Y., Jpn. J. Cancer Res. 92 (6), 592-596 (2001)Suzuki,T., Genes Cells 6 (2), 131-138 (2001)Ikematsu,N., Oncogene 18 (52), 7432-7441 (1999)
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