TOB2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q14106 |
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Clone Names | 70319119 |
Gene ID | 10766 |
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Other Names | Protein Tob2, Protein Tob4, Transducer of erbB-2 2, TOB2, KIAA1663, TOB4, TROB2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6274a was selected from the N-term region of human TOB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TOB2 |
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Synonyms | KIAA1663, TOB4, TROB2 |
Function | Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases. |
Cellular Location | Cytoplasm. |
Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TOB2 belongs to the TOB /BTG1 family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.
References
Sasajima,H., Eur. J. Biochem. 269 (14), 3596-3604 (2002)Yoshida,Y., Jpn. J. Cancer Res. 92 (6), 592-596 (2001)Suzuki,T., Genes Cells 6 (2), 131-138 (2001)Ikematsu,N., Oncogene 18 (52), 7432-7441 (1999)
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