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AKIP Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NWT8 |
|---|---|
| Clone Names | 80808144 |
| Gene ID | 54998 |
|---|---|
| Other Names | Aurora kinase A-interacting protein, AURKA-interacting protein, 28S ribosomal protein S38, mitochondrial, MRP-S38, AURKAIP1, AIP, AKIP, MRPS38 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6512b was selected from the C-term region of human AKIP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AURKAIP1 |
|---|---|
| Synonyms | AIP, AKIP, MRPS38 |
| Function | May act as a negative regulator of Aurora-A kinase, by down- regulation through proteasome-dependent degradation. |
| Cellular Location | Mitochondrion matrix. Nucleus |
| Tissue Location | Ubiquitously expressed and especially highly expressed in heart, skeletal muscle and testis |
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Provided below are standard protocols that you may find useful for product applications.
Background
AKIP may act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.
References
Wysong,D.R., Cell Cycle 8 (6), 876-888 (2009)Chan,E.H., Chromosoma 117 (5), 457-469 (2008)Fumoto,K., Oncogene 27 (32), 4478-4487 (2008)
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