|Other Names||Aurora kinase A-interacting protein, AURKA-interacting protein, 28S ribosomal protein S38, mitochondrial, MRP-S38, AURKAIP1, AIP, AKIP, MRPS38|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6512b was selected from the C-term region of human AKIP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||AIP, AKIP, MRPS38|
|Function||May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.|
|Cellular Location||Mitochondrion. Nucleus|
|Tissue Location||Ubiquitously expressed and especially highly expressed in heart, skeletal muscle and testis|
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Provided below are standard protocols that you may find useful for product applications.
AKIP may act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.
Wysong,D.R., Cell Cycle 8 (6), 876-888 (2009)Chan,E.H., Chromosoma 117 (5), 457-469 (2008)Fumoto,K., Oncogene 27 (32), 4478-4487 (2008)
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