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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   HFE Antibody (N-term) Blocking Peptide   

HFE Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q30201
Clone Names 80703085
Peptide ID 80703085
Additional Information
Gene ID 3077
Other Names Hereditary hemochromatosis protein, HLA-H, HFE, HLAH
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6544a was selected from the N-term region of human HFE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HFE
Synonyms HLAH
Function Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in all tissues tested except brain.
Research Areas
Citations (0)

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HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.


Valenti,L., Clin J Am Soc Nephrol 4 (8), 1331-1337 (2009)Won,J.E., Intervirology 52 (5), 239-246 (2009)

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$ 80.00
Cat# BP6544a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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