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HFE Antibody (N-term) Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP6544a | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
HFE Antibody (N-term) Blocking Peptide - Product info | |
| Primary Accession | Q30201 |
| Clone Names | 80703085 |
| Calculated MW | 40108 Da |
HFE Antibody (N-term) Blocking Peptide - Additional info | |
| Gene ID 3077 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP6544a was selected from the N-term region of human HFE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
HFE Antibody (N-term) Blocking Peptide - Protein Information | |
| Name HFE | |
| Synonyms HLAH | |
| Function Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin | |
| Cellular Location Membrane; Single-pass type I membrane protein | |
| Tissue Location Expressed in all tissues tested except brain. | |
HFE Antibody (N-term) Blocking Peptide - Related products
AP6544a: HFE Antibody (N-term)
AP6544c: HFE Antibody (Center)
LY12138a: HFE Over-expression Lysate
BP6544a: HFE Antibody (N-term) Blocking Peptide
HFE Antibody (N-term) Blocking Peptide - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
REFERENCES
Valenti,L., Clin J Am Soc Nephrol 4 (8), 1331-1337 (2009)Won,J.E., Intervirology 52 (5), 239-246 (2009)
