|Other Names||Angiopoietin-related protein 2, Angiopoietin-like protein 2, ANGPTL2, ARP2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6547b was selected from the C-term region of human ANGPTL2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Induces sprouting in endothelial cells through an autocrine and paracrine action.|
|Tissue Location||Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate|
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Provided below are standard protocols that you may find useful for product applications.
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.
Kikuchi,R., Cancer Res. 68 (13), 5067-5075 (2008)Sun,H., Nephron Exp. Nephrol. 105 (4), E117-E123 (2007)
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