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AGO1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UL18
Clone Names 80703059
Peptide ID 80703059
Additional Information
Gene ID 26523
Other Names Protein argonaute-1, Argonaute1, hAgo1, Argonaute RISC catalytic component 1, Eukaryotic translation initiation factor 2C 1, eIF-2C 1, eIF2C 1, Putative RNA-binding protein Q99, AGO1, EIF2C1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6558a was selected from the N-term region of human AGO1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGO1
Synonyms EIF2C1
Function Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).
Cellular Location Cytoplasm, P-body
Research Areas
Citations (0)

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AGO1 is a member of the Argonaute family of proteins which play a role in RNA interference. The protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing.


Weinmann,L., Cell 136 (3), 496-507 (2009)Horikawa,Y., Clin. Cancer Res. 14 (23), 7956-7962 (2008)

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$ 80.00
Cat# BP6558a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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