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CTSE Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P14091
Clone Names 80513072
Peptide ID 80513072
Additional Information
Gene ID 1510
Other Names Cathepsin E, Cathepsin E form I, Cathepsin E form II, CTSE
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6568c was selected from the Center region of human CTSE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
Cellular Location Endosome. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome
Tissue Location Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B- lymphocytes.
Research Areas
Citations (0)

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CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.


Caruso,M., Virchows Arch. 454 (3), 291-302 (2009)Burster,T., Biochem. Biophys. Res. Commun. 377 (4), 1299-1303 (2008)

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$ 80.00
Cat# BP6568c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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