|Other Names||Annexin A4, 35-beta calcimedin, Annexin IV, Annexin-4, Carbohydrate-binding protein p33/p41, Chromobindin-4, Endonexin I, Lipocortin IV, P325, PP4-X, Placental anticoagulant protein II, PAP-II, Protein II, ANXA4, ANX4|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6599a was selected from the N-term region of human ANXA4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.|
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Provided below are standard protocols that you may find useful for product applications.
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. Isolated from human placenta, ANX4 is a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.
Skrahina,T., Exp. Cell Res. 314 (5), 1039-1047 (2008)Ulander,V.M., Thromb. Res. 120 (6), 865-870 (2007)
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