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BZRP Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P30536
Clone Names 80924087
Peptide ID 80924087
Additional Information
Gene ID 706
Other Names Translocator protein, Mitochondrial benzodiazepine receptor, PKBS, Peripheral-type benzodiazepine receptor, PBR, TSPO, BZRP, MBR
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6606b was selected from the C-term region of human BZRP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BZRP, MBR
Function Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678).
Cellular Location Mitochondrion membrane; Multi-pass membrane protein
Tissue Location Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
Research Areas
Citations (0)

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Present mainly in the mitochondrial compartment of peripheral tissues, the protein BZRP interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis.


Cosenza-Nashat,M., Neuropathol. Appl. Neurobiol. 35 (3), 306-328 (2009)Karry,R., Pharmacogenet. Genomics 18 (11), 977-988 (2008)

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$ 80.00
Cat# BP6606b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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