|Other Names||Clusterin-associated protein 1, Qilin, CLUAP1, KIAA0643|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6632c was selected from the Center region of human CLUAP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity).|
|Cellular Location||Nucleus. Cell projection, cilium.|
|Tissue Location||Expressed in testis, thyroid and trachea and to a lower extent in spinal cord and adrenal gland. Highly expressed in colon cancer and osteosarcoma cell lines|
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Provided below are standard protocols that you may find useful for product applications.
CLUAP1 may play a role in cell proliferation or apoptosis.
Ishikura,H., Int. J. Oncol. 30 (2), 461-467 (2007)Takahashi,M., Oncogene 23 (57), 9289-9294 (2004)
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