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GLS2 Antibody (C-term R471) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UI32
Clone Names 81020124
Peptide ID 81020124
Additional Information
Gene ID 27165
Other Names Glutaminase liver isoform, mitochondrial, GLS, L-glutaminase, L-glutamine amidohydrolase, GLS2, GA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6650b was selected from the C-term region of human GLS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLS2
Synonyms GA
Function Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
Cellular Location Mitochondrion.
Tissue Location Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas.
Research Areas
Citations (0)

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GLS2 is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well.


Szeliga,M., Glia 57 (9), 1014-1023 (2009)Maeshima,H., Prog. Neuropsychopharmacol. Biol. Psychiatry 31 (7), 1410-1418 (2007)

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$ 80.00
Cat# BP6650b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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