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KRT14 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P02533
Clone Names 80917040
Peptide ID 80917040
Additional Information
Gene ID 3861
Other Names Keratin, type I cytoskeletal 14, Cytokeratin-14, CK-14, Keratin-14, K14, KRT14
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6713c was selected from the Center region of human KRT14. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT14
Function The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Cellular Location Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern
Tissue Location Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.
Research Areas
Citations (0)

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KRT14 is a member of the keratin family, the most diverse group of intermediate filaments. This protein, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells.


Barcelos,A.C., J. Cutan. Pathol. 36 (6), 647-654 (2009)Romano,R.A., PLoS ONE 4 (5), E5623 (2009)

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$ 80.00
Cat# BP6713c
(40 western blots)
Availability: In Stock
Bulk Size
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