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CPD Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O75976
Clone Names 80410136
Peptide ID 80410136
Additional Information
Gene ID 1362
Other Names Carboxypeptidase D, Metallocarboxypeptidase D, gp180, CPD
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6725b was selected from the C-term region of human CPD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPD
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q90240}; Single-pass type I membrane protein
Tissue Location Highly expressed in placenta, pancreas and hepatoma cells. Lower levels found in skeletal muscle, heart and colon carcinoma and melanoma cell lines
Research Areas
Citations (0)

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Background

The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein.

References

Hoff,N.P., J. Clin. Immunol. 27 (6), 568-579 (2007)O'Malley,P.G., Biochem. J. 390 (PT 3), 665-673 (2005)

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$ 80.00
Cat# BP6725b
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