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CPD Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O75976 |
|---|---|
| Clone Names | 80410136 |
| Gene ID | 1362 |
|---|---|
| Other Names | Carboxypeptidase D, Metallocarboxypeptidase D, gp180, CPD |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6725b was selected from the C-term region of human CPD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CPD |
|---|---|
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q90240}; Single-pass type I membrane protein |
| Tissue Location | Highly expressed in placenta, pancreas and hepatoma cells. Lower levels found in skeletal muscle, heart and colon carcinoma and melanoma cell lines |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein.
References
Hoff,N.P., J. Clin. Immunol. 27 (6), 568-579 (2007)O'Malley,P.G., Biochem. J. 390 (PT 3), 665-673 (2005)
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