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EMAL1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O00423
Clone Names 80808088
Peptide ID 80808088
Additional Information
Gene ID 2009
Other Names Echinoderm microtubule-associated protein-like 1, EMAP-1, HuEMAP-1, EML1, EMAP1, EMAPL, EMAPL1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6733c was selected from the Center region of human EMAL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EML1
Function Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se (By similarity).
Cellular Location Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Note=Detected in cytoplasmic punctae. Co-localizes with microtubules. Enriched in perinuclear regions during interphase and in the region of spindle microtubules during metaphase. Enriched at the midzone during telophase and cytokinesis. Detected at growth cones in neurons (By similarity)
Tissue Location Ubiquitous; expressed in most tissues with the exception of thymus and peripheral blood lymphocytes
Research Areas
Citations (0)

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Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form.


Ly,C.D., Biochem. Biophys. Res. Commun. 291 (1), 85-90 (2002)Lepley,D.M., Gene 237 (2), 343-349 (1999)

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$ 80.00
Cat# BP6733c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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