|Other Names||Echinoderm microtubule-associated protein-like 2, EMAP-2, HuEMAP-2, EML2, EMAP2, EMAPL2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6734a was selected from the N-term region of human EMAL2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules.|
|Cellular Location||Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with the microtubule cytoskeleton. Colocalizes with the mitotic spindle|
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Provided below are standard protocols that you may find useful for product applications.
EMAL2 may modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
Eichenmuller,B., J. Biol. Chem. 277 (2), 1301-1309 (2002)Lepley,D.M., Gene 237 (2), 343-349 (1999)
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