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SEMA3B Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q13214 |
|---|---|
| Clone Names | 80924195 |
| Gene ID | 7869 |
|---|---|
| Other Names | Semaphorin-3B, Sema A(V), Semaphorin-V, Sema V, SEMA3B, SEMA5, SEMAA |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6742b was selected from the C-term region of human SEMA3B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SEMA3B |
|---|---|
| Synonyms | SEMA5, SEMAA |
| Function | Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. |
| Cellular Location | Secreted. Endoplasmic reticulum. Note=Accumulates in the endoplasmic reticulum |
| Tissue Location | Expressed abundantly but differentially in a variety of neural and nonneural tissues |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis.
References
Beuten,J., J. Urol. 182 (4), 1614-1620 (2009)Castro-Rivera,E., Cancer Res. 68 (20), 8295-8303 (2008)
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