TTC19 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6DKK2 |
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Clone Names | 80924263 |
Gene ID | 54902 |
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Other Names | Tetratricopeptide repeat protein 19, mitochondrial, TPR repeat protein 19, TTC19 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6744b was selected from the C-term region of human TTC19. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TTC19 |
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Function | Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1 (PubMed:21278747, PubMed:28673544). Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation of UQCRFS1 into the complex III and whose presence is detrimental for its catalytic activity (PubMed:28673544). |
Cellular Location | Mitochondrion inner membrane |
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Provided below are standard protocols that you may find useful for product applications.
References
Tsang,H.T., Genomics 88 (3), 333-346 (2006)
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