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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TRMT5 Antibody (N-term) Blocking Peptide   

TRMT5 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q32P41
Clone Names 81110065
Peptide ID 81110065
Additional Information
Gene ID 57570
Other Names tRNA (guanine(37)-N1)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152}, 211228 {ECO:0000255|HAMAP-Rule:MF_03152}, M1G-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152}, tRNA [GM37] methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152}, tRNA methyltransferase 5 homolog {ECO:0000255|HAMAP-Rule:MF_03152}, TRMT5 {ECO:0000255|HAMAP-Rule:MF_03152}
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6746a was selected from the N-term region of human TRMT5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRMT5 {ECO:0000255|HAMAP-Rule:MF_03152}
Function Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
Cellular Location Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03152}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03152} Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03152}. Note=Predominantly in the mitochondria and in the nucleus. {ECO:0000255|HAMAP- Rule:MF_03152}
Research Areas
Citations (0)

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tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine.


Brule,H., Biochemistry 43 (28), 9243-9255 (2004)

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$ 80.00
Cat# BP6746a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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