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CRHR2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q13324
Clone Names 80513060
Peptide ID 80513060
Additional Information
Gene ID 1395
Other Names Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6787c was selected from the Center region of human CRHR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRHR2
Synonyms CRF2R, CRH2R
Function G-protein coupled receptor for CRH (corticotropin- releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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CRHR2 is a receptor for corticotropin releasing factor.It Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.


Yerges,L.M.,, J. Bone Miner. Res. (2009)

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$ 80.00
Cat# BP6787c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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