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FMO3 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P31513
Clone Names 90121123
Peptide ID 90121123
Additional Information
Gene ID 2328
Other Names Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline oxidase 3, FMO II, FMO form 2, Hepatic flavin-containing monooxygenase 3, FMO 3, Trimethylamine monooxygenase, FMO3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6901a was selected from the N-term region of human FMO3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FMO3
Function Involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. Plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds (PubMed:9224773).
Cellular Location Microsome membrane. Endoplasmic reticulum membrane
Tissue Location Liver.
Research Areas
Citations (0)

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Background

FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds.

References

Allerston,C.K., et.al., Mol. Genet. Metab. 98 (1-2), 198-202 (2009)

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$ 80.00
Cat# BP6901a
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