|Other Names||Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21, CR2, C3DR|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6965b was selected from the C-term region of human CR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen|
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Provided below are standard protocols that you may find useful for product applications.
CR2 is a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes.
Rikova,K., et.al., Cell 131 (6), 1190-1203 (2007)
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