CR2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P20023 |
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Clone Names | 90504056 |
Gene ID | 1380 |
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Other Names | Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21, CR2, C3DR |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6965b was selected from the C-term region of human CR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CR2 |
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Synonyms | C3DR |
Function | Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047). Participates in B lymphocytes activation (PubMed:7753047). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen |
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Provided below are standard protocols that you may find useful for product applications.
Background
CR2 is a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes.
References
Rikova,K., et.al., Cell 131 (6), 1190-1203 (2007)
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