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> home > Products > Peptides > Biological Process > Embryonic Development > FTO Antibody (N-term) Blocking Peptide
FTO Antibody (N-term) Blocking PeptideSynthetic peptide
| Country | United States
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| Catalog # | Size | Availability | Price | |
| BP6976a | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
FTO Antibody (N-term) Blocking Peptide - Product info | |
| Primary Accession | Q9C0B1 |
| Clone Names | 90713066 |
| Calculated MW | 58282 Da |
FTO Antibody (N-term) Blocking Peptide - Additional info | |
| Gene ID 79068 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP6976a was selected from the N-term region of human FTO. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
FTO Antibody (N-term) Blocking Peptide - Protein Information | |
| Name FTO | |
| Synonyms KIAA1752 | |
| Function Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single- stranded RNA containing 3-methyluracil, followed by single- stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation | |
| Cellular Location Nucleus (By similarity). | |
| Tissue Location Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary | |
FTO Antibody (N-term) Blocking Peptide - Related products
FTO Antibody (N-term) Blocking Peptide - Research Areas
PeptidesBiological ProcessEmbryonic DevelopmentMulticellular Organismal DevelopmentAnatomical Structure DevelopmentDevelopmental ProcessAnatomical Structure MorphogenesisPattern Specification ProcessMulticellular Organismal ProcessEmbryonic MorphogenesisAppendage DevelopmentLimb DevelopmentLimb MorphogenesisAppendage MorphogenesisEmbryonic Limb MorphogenesisEmbryonic Appendage Morphogenesis
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The precise function of FTO remains to be determined.
REFERENCES
Scott,L.J., et.al., Science 316 (5829), 1341-1345 (2007)
