|Other Names||GTPase IMAP family member 5, Immunity-associated nucleotide 4-like 1 protein, Immunity-associated nucleotide 5 protein, IAN-5, hIAN5, Immunity-associated protein 3, GIMAP5, IAN4L1, IAN5, IMAP3|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6984c was selected from the Center region of human GIMAP5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||IAN4L1, IAN5, IMAP3|
|Function||Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity).|
|Cellular Location||Mitochondrion outer membrane; Single-pass type IV membrane protein. Lysosome|
|Tissue Location||Widely expressed with high levels in lymph node and spleen. High expression found in CD4 and CD8-positive T- cells and monocytes with very low levels in B-lymphocytes. Highly expressed in B-lymphocyte-derived neoplasms|
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Provided below are standard protocols that you may find useful for product applications.
GIMAP5 is a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins.
Shin,J.H., et.al., Genes Immun. 8 (6), 503-512 (2007)
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