|Other Names||Dynactin subunit 5, Dynactin subunit p25, DCTN5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6988c was selected from the Center region of human DCTN5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore|
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Provided below are standard protocols that you may find useful for product applications.
Dynactin is a multimeric protein essential for minus-end-directed transport driven by the microtubule-based motor dynein. DCTN5 is a subunit of the pointed-end subcomplex of dynactin that is thought to interact with membranous cargo.
Parisi,G., et.al., FEBS Lett. 562 (1-3), 1-4 (2004)
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