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DCTN5 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BTE1 |
|---|---|
| Clone Names | 90713052 |
| Gene ID | 84516 |
|---|---|
| Other Names | Dynactin subunit 5, Dynactin subunit p25, DCTN5 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6988c was selected from the Center region of human DCTN5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DCTN5 (HGNC:24594) |
|---|---|
| Function | Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0A286ZK88}. Chromosome, centromere, kinetochore |
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Provided below are standard protocols that you may find useful for product applications.
Background
Dynactin is a multimeric protein essential for minus-end-directed transport driven by the microtubule-based motor dynein. DCTN5 is a subunit of the pointed-end subcomplex of dynactin that is thought to interact with membranous cargo.
References
Parisi,G., et.al., FEBS Lett. 562 (1-3), 1-4 (2004)
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