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KIST (KIS) Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8TAS1
Other Accession NP_787062
Clone Names 4012109
Peptide ID 4012109
Additional Information
Gene ID 127933
Other Names Serine/threonine-protein kinase Kist, Kinase interacting with stathmin, PAM COOH-terminal interactor protein 2, P-CIP2, U2AF homology motif kinase 1, UHMK1, KIS, KIST
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7063b was selected from the C-term region of human KIST. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UHMK1
Synonyms KIS, KIST
Function Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).
Cellular Location Nucleus.
Tissue Location Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes
Research Areas
Citations (0)

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KIST, a member of the Ser/Thr protein kinase family, is a pyruvate kinase that catalyzes formation of phosphoenolpyruvate from pyruvate and ATP. A role for the primarily nuclear KIST protein in mediation of cellular metabolism has been postulated based on the interaction identified with thyroid hormone. KIST is widely expressed, with highest abundance in skeletal muscle, kidney, placenta and peripheral blood leukocytes. Upon serum stimulation, KIST phosphorylates CDKN1B/p27Kip1, thereby regulating the subcellular location of CDKN1B and cell cycle progression in the G1 phase. KIST, which contains one RNA recognition motif domain, has been proposed to partipate in trafficking and processing of RNA. KIST binds to Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells.


Bieche, I., et al., Brain Res. Mol. Brain Res. 114(1):55-64 (2003).Boehm, M., et al., EMBO J. 21(13):3390-3401 (2002).Caldwell, B.D., et al., J. Biol. Chem. 274(49):34646-34656 (1999).

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$ 80.00
Cat# BP7063b
Availability: In Stock
Bulk Size
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