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CARKL Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UHJ6
Clone Names 4010805
Peptide ID 4010805
Additional Information
Gene ID 23729
Other Names Sedoheptulokinase, SHK, Carbohydrate kinase-like protein, SHPK, CARKL
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7089a was selected from the N-term region of human CARKL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CARKL
Function Acts as a modulator of macrophage activation through control of glucose metabolism.
Cellular Location Cytoplasm.
Tissue Location Strongly expressed in liver, kidney and pancreas. Expressed at lower levels in placenta and heart. Very weakly expressed in lung and brain.
Research Areas
Citations (0)

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Carbohydrate kinase-like (CARKL) has contains motifs showing weak similarity to 2 domains of the FGGY family of carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this protein and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene for CARKL resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. This protein is strongly expressed in liver, kidney and pancreas, at lower levels in placenta and heart, and neglibly in lung and brain.

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$ 80.00
Cat# BP7089a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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