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GUCY1B2 Antibody(C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O75343
Clone Names 5030108
Peptide ID 5030108
Additional Information
Other Names Guanylate cyclase soluble subunit beta-2, GCS-beta-2, GUCY1B2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7135b was selected from the C-term region of human GUCY1B2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GUCY1B2
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.


Behrends, S., et al., Biochem. Biophys. Res. Commun. 271(1):64-69 (2000).Behrends, S., et al., Biochem. Pharmacol. 59(6):713-717 (2000).Bellamy, T.C., et al., Proc. Natl. Acad. Sci. U.S.A. 97(6):2928-2933 (2000).Behrends, S., et al., Genomics 55(1):126-127 (1999).Yuen, P.S., et al., Biochemistry 29(49):10872-10878 (1990).

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$ 80.00
Cat# BP7135b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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