|Other Names||Homeodomain-interacting protein kinase 4, HIPK4|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7138a was selected from the N-term region of human HIPK4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors (Potential).|
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Provided below are standard protocols that you may find useful for product applications.
HIPK4 is a serine/threonine protein kinase that may act as a corepressor of transcription factors.
Ota, T., et al., Nat. Genet. 36(1):40-45 (2004).
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