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STK22B Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96PF2
Clone Names 4012823
Peptide ID 4012823
Additional Information
Gene ID 23617
Other Names Testis-specific serine/threonine-protein kinase 2, TSK-2, TSK2, TSSK-2, Testis-specific kinase 2, DiGeorge syndrome protein G, DGS-G, Serine/threonine-protein kinase 22B, TSSK2, DGSG, SPOGA2, STK22B
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7190a was selected from the N-term region of human STK22B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TSSK2
Synonyms DGSG, SPOGA2, STK22B
Function Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Present in the cytoplasm of elongating spermatids. In spermatozoa, localizes in the equatorial segment, neck, the midpiece and in a specific sperm head compartment (By similarity). In spermatids, concentrates in centrioles during flagellogenesis.
Tissue Location Testis-specific. Present in mature spermatozoa (at protein level).
Research Areas
Citations (0)

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STK22B is involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. This protein may play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies.


Hao, Z., et al., Mol. Hum. Reprod. 10(6):433-444 (2004).Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Dunham, I., et al., Nature 402(6761):489-495 (1999).Gong, W., et al., Hum. Mol. Genet. 5(6):789-800 (1996).Collins, J.E., et al., Genome Biol. 5 (10), R84 (2004) (): ().

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$ 80.00
Cat# BP7190a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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