|Other Names||Serine/threonine-protein kinase 35, CLP-36-interacting kinase 1, CLIK-1, PDLIM1-interacting kinase 1, Serine/threonine-protein kinase 35 L1, STK35, CLIK1, PDIK1, STK35L1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7243c was selected from the Center region of human STK35 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CLIK1, PDIK1, STK35L1|
|Cellular Location||Nucleus. Nucleus, nucleolus. Cytoplasm. Note=When associated with PDLIM1, it is mostly found in cytoplasm, localized to actin stress fibers (PubMed:11973348). However, PubMed:19756140 detected STK35 only in the nucleus, and the presence of PDLIM1 had no influence on its location|
|Tissue Location||Expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
STK35 can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. This kinase may be a regulator of actin stress fibers in nonmuscle cells. This protein has also been found in the nucleus.
Vallenius, T., et al., J. Cell. Sci. 115 (Pt 10), 2067-2073 (2002).
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