HMX2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P43687 |
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Other Accession | NP_666110 |
Clone Names | 6071529 |
Gene ID | 15372 |
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Other Names | Homeobox protein HMX2, Homeobox protein Nkx-52, Hmx2, Nkx-52, Nkx5-2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7266a was selected from the N-term region of human HMX2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Hmx2 |
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Synonyms | Nkx-5.2, Nkx5-2 |
Function | Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in the developing CNS, including a specific expression in vestibular structures throughout inner ear development. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Homeobox genes represent a class of transcription factors that play key roles in the regulation of embryogenesis and development. Here we report the identification of a homeobox-containing gene family that is highly conserved at both the nucleotide and amino acid levels in a diverse number of species. These species encompass both vertebrate and invertebrate phylogenies, ranging from Homo sapiens to Drosophila melanogaster.
References
Wang,W., Dev. Cell 7 (3), 439-453 (2004)
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