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MSRA Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UJ68
Clone Names 80902036
Peptide ID 80902036
Additional Information
Gene ID 4482
Other Names Mitochondrial peptide methionine sulfoxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase, Protein-methionine-S-oxide reductase, PMSR, MSRA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7321a was selected from the N-term region of human MSRA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSRA
Function Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Cellular Location Isoform 1: Mitochondrion. Isoform 3: Cytoplasm. Nucleus.
Tissue Location Ubiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus
Research Areas
Citations (0)

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Background

MSRA is ubiquitous and highly conserved. This protein carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein's proposed function is the repair of oxidative damage to proteins to restore biological activity.

References

Pascual,I., Larrayoz,I.M. Genomics 93 (1), 62-71 (2009)Schallreuter,K.U., Rubsam,K. J. Invest. Dermatol. 128 (4), 808-815 (2008)Picot,C.R., Perichon,M. FEBS Lett. 558 (1-3), 74-78 (2004)Vougier,S., Mary,J. Biochem. J. 373 (PT 2), 531-537 (2003)

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$ 80.00
Cat# BP7321a
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