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NEFL Antibody (Center R185) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P07196
Clone Names 80703095
Peptide ID 80703095
Additional Information
Gene ID 4747
Other Names Neurofilament light polypeptide, NF-L, 68 kDa neurofilament protein, Neurofilament triplet L protein, NEFL, NF68, NFL
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7332c was selected from the Center region of human NEFL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms NF68, NFL
Function Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
Research Areas
Citations (0)

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NEFL is type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. This protein comprises the axoskeleton and it functionally maintains the neuronal caliber. The protein may also play a role in intracellular transport to axons and dendrites. Mutations in this protein cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies.


Martins-de-Souza,D., Gattaz,W.F. J. Neural Transm. 116 (3), 275-289 (2009)Shin,J.S., Chung,K.W. J. Hum. Genet. 53 (10), 936-940 (2008)Dong,D.L., Xu,Z.S. J. Biol. Chem. 268 (22), 16679-16687 (1993)Hurst,J., Flavell,D. Cytogenet. Cell Genet. 45 (1), 30-32 (1987)

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$ 80.00
Cat# BP7332c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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