CA1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P00915 |
---|---|
Clone Names | 80411135 |
Gene ID | 759 |
---|---|
Other Names | Carbonic anhydrase 1, Carbonate dehydratase I, Carbonic anhydrase B, CAB, Carbonic anhydrase I, CA-I, CA1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7352c was selected from the Center region of human CA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CA1 |
---|---|
Function | Catalyzes the reversible hydration of carbon dioxide (PubMed:10550681, PubMed:18618712, PubMed:16807956, PubMed:16686544, PubMed:17127057, PubMed:19186056, PubMed:19206230, PubMed:16506782, PubMed:17314045, PubMed:17407288). Can hydrate cyanamide to urea (PubMed:10550681). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:B0BNN3}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it is a cytosolic protein which is found at the highest level in erythrocytes.
References
Gambhir,K.K., Biochem. Genet. 45 (5-6), 431-439 (2007)Temperini,C., Bioorg. Med. Chem. Lett. 17 (8), 2210-2215 (2007)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.