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CYK18 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P05783
Clone Names 80821011
Peptide ID 80821011
Additional Information
Gene ID 3875
Other Names Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7376c was selected from the Center region of human CYK18. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT18
Synonyms CYK18
Function Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Cellular Location Cytoplasm, perinuclear region. Nucleus, nucleolus
Tissue Location Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Research Areas
Citations (0)

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KRT18 is the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament family. They are expressed in single layer epithelial tissues of the body. Mutations in its gene have been linked to cryptogenic cirrhosis.


Zhang,Q., Clin. Cancer Res. 15 (10), 3557-3567 (2009)Kruse,R., Folia Histochem. Cytobiol. 47 (1), 127-130 (2009)Toivola,D.M., Hepatology 40 (2), 459-466 (2004)

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$ 80.00
Cat# BP7376c
(40 western blots)
Availability: In Stock
Bulk Size
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