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CTSS Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P25774 |
|---|---|
| Clone Names | 80513088 |
| Gene ID | 1520 |
|---|---|
| Other Names | Cathepsin S, CTSS |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CTSS |
|---|---|
| Function | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation (PubMed:30612035). The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. |
| Cellular Location | Lysosome. Secreted. Cytoplasmic vesicle, phagosome |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein CTSS, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The protein can function as an elastase over a broad pH range in alveolar macrophages.
References
Lindahl,C., Cancer Genomics Proteomics 6 (3), 149-159 (2009)Bunatova,K., Int. J. Biol. Markers 24 (1), 47-51 (2009)
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