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CRHBP Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P24387
Clone Names 81006053
Peptide ID 81006053
Additional Information
Gene ID 1393
Other Names Corticotropin-releasing factor-binding protein, CRF-BP, CRF-binding protein, Corticotropin-releasing hormone-binding protein, CRH-BP, CRHBP, CRFBP
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7431b was selected from the C-term region of human CRHBP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CRFBP
Function Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Cellular Location Secreted.
Research Areas
Citations (0)

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Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein (CRHBP) which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.


Behan D.P., Potter E., Lewis K.A.Genomics 16:63-68(1993)Fischer W.H., Behan D.P., Park M.J. Biol. Chem. 269:4313-4316(1994)

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$ 80.00
Cat# BP7431b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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