|Other Names||Golgi SNAP receptor complex member 2, 27 kDa Golgi SNARE protein, Membrin, GOSR2, GS27|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7433a was selected from the N-term region of human GOSR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in transport of proteins from the cis/medial- Golgi to the trans-Golgi network.|
|Cellular Location||Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein Golgi apparatus membrane. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus (By similarity).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
GOSR2 is a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this protein may be involved in familial essential hypertension.
Lowe S.L., Peter F., Subramaniam V.N.Nature 389:881-884(1997)Bui T.D., Levy E.R., Subramaniam V.N.Genomics 57:285-288(1999)
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