|Other Names||Golgi SNAP receptor complex member 2, 27 kDa Golgi SNARE protein, Membrin, GOSR2, GS27|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7433a was selected from the N-term region of human GOSR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in transport of proteins from the cis/medial- Golgi to the trans-Golgi network.|
|Cellular Location||Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein Golgi apparatus membrane. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
GOSR2 is a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this protein may be involved in familial essential hypertension.
Lowe S.L., Peter F., Subramaniam V.N.Nature 389:881-884(1997)Bui T.D., Levy E.R., Subramaniam V.N.Genomics 57:285-288(1999)
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