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CA4 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P22748
Peptide ID 80411148
Additional Information
Gene ID 762
Other Names Carbonic anhydrase 4, Carbonate dehydratase IV, Carbonic anhydrase IV, CA-IV, CA4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CA4
Function Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Location Expressed in the endothelium of the choriocapillaris in eyes (at protein level). Not expressed in the retinal epithelium at detectable levels
Research Areas
Citations (0)

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CA4 is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This protein is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, the protein may have a role in inherited renal abnormalities of bicarbonate transport.


Okuyama T., Sato S.Proc. Natl. Acad. Sci. U.S.A. 89:1315-1319(1992)Okuyama T.Genomics 16:678-684(1993)Yang Z., Alvarez B.V.Hum. Mol. Genet. 14:255-265(2005)Okuyama T.Arch. Biochem. Biophys. 320:315-322(1995)

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$ 80.00
Cat# BP7479d
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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