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Thrombopoietin (TPO) Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P40225
Clone Names 71213148
Peptide ID 71213148
Additional Information
Gene ID 7066
Other Names Thrombopoietin, C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand, THPO, MGDF
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7557b was selected from the C-term region of human THPO. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MGDF
Function Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Cellular Location Secreted.
Research Areas
Citations (0)

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Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. It is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.


Baker,J.E.,Cardiovasc. Res. 77 (1), 44-53 (2008)Steinberg,O.,J. Pediatr. Hematol. Oncol. 29 (12), 822-825 (2007)Kanayasu-Toyoda,T.,J. Biol. Chem. 282 (46), 33507-33514 (2007)

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$ 80.00
Cat# BP7557b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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