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C1RL Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NZP8
Clone Names 80411130
Peptide ID 80411130
Additional Information
Gene ID 51279
Other Names Complement C1r subcomponent-like protein, C1r-LP, C1r-like protein, 3421-, C1r-like serine protease analog protein, CLSPa, C1RL, C1RL1, C1RLP, CLSPA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7603a was selected from the N-term region of human C1RL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name C1RL
Synonyms C1RL1, C1RLP, CLSPA
Function Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
Cellular Location Secreted.
Tissue Location Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV- 3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level)
Research Areas
Citations (0)

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C1RL mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.


Lin,N., Liu,S. Biochem. Biophys. Res. Commun. 321 (2), 329-336 (2004)Wicher,K.B. Proc. Natl. Acad. Sci. U.S.A. 101 (40), 14390-14395 (2004)Cerhan,J.R., Novak,A.J. Br. J. Haematol. (2009) In press

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$ 80.00
Cat# BP7603a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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