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PCSK2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P16519
Clone Names 80917124
Peptide ID 80917124
Additional Information
Gene ID 5126
Other Names Neuroendocrine convertase 2, NEC 2, KEX2-like endoprotease 2, Prohormone convertase 2, Proprotein convertase 2, PC2, PCSK2, NEC2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7617a was selected from the N-term region of human PCSK2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PCSK2
Synonyms NEC2
Function Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.
Cellular Location Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules
Research Areas
Citations (0)

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PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone.


Leak,T.S., Keene,K.L. Mol. Genet. Metab. 92 (1-2), 145-150 (2007)Shen,X., Li,Q.L. Am. J. Physiol. Endocrinol. Metab. 288 (1), E236-E245 (2005)Tzimas,G.N., Chevet,E. BMC Cancer 5, 149 (2005)Seidah,N.G., Mattei,M.G. Genomics 11 (1), 103-107 (1991)

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$ 80.00
Cat# BP7617a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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