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NAB2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q15742
Peptide ID 80917086
Additional Information
Gene ID 4665
Other Names NGFI-A-binding protein 2, EGR-1-binding protein 2, Melanoma-associated delayed early response protein, Protein MADER, NAB2, MADER
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NAB2
Synonyms MADER
Function Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity).
Cellular Location Nucleus. Note=Isoform 2 is not localized to the nucleus.
Tissue Location Widely expressed at low levels. Highly expressed in melanoma cell lines
Research Areas
Citations (0)

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NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by this protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex.


Srinivasan,R., J. Biol. Chem. 281 (22), 15129-15137 (2006)Kumbrink,J., J. Biol. Chem. 280 (52), 42785-42793 (2005)Lucerna,M., J. Biol. Chem. 278 (13), 11433-11440 (2003)

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$ 80.00
Cat# BP7635a
(40 western blots)
Availability: In Stock
Bulk Size
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