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DOK5 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9P104
Clone Names 4061502
Peptide ID 4061502
Additional Information
Gene ID 55816
Other Names Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6, DOK5, C20orf180
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7693c was selected from the Center region of human DOK5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DOK5
Synonyms C20orf180
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Tissue Location Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes.
Research Areas
Citations (0)

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DOK5 is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.


Cai, D., et al., J. Biol. Chem. 278(28):25323-25330 (2003).Favre, C., et al., Genes Immun. 4(1):40-45 (2003).

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$ 80.00
Cat# BP7693c
(40 western blots)
Availability: In Stock
Bulk Size
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