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SEMA3A Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q14563
Clone Names 71213143
Peptide ID 71213143
Additional Information
Gene ID 10371
Other Names Semaphorin-3A, Semaphorin III, Sema III, SEMA3A, SEMAD
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7760c was selected from the Center region of human SEMA3A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SEMAD
Function Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1.
Cellular Location Secreted.
Research Areas
Citations (0)

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SEMA3A is a member of the semaphorin family with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.


Narazaki,M., Blood 111 (8), 4126-4136 (2008)Tannemaat,M.R., J. Neurosci. 27 (52), 14260-14264 (2007)Appleton,B.A., EMBO J. 26 (23), 4902-4912 (2007)

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$ 80.00
Cat# BP7760c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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