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SCRG1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O75711 |
|---|---|
| Clone Names | 70411236 |
| Gene ID | 11341 |
|---|---|
| Other Names | Scrapie-responsive protein 1, Scrapie-responsive gene 1 protein, ScRG-1, SCRG1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7784c was selected from the Center region of human SCRG1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SCRG1 |
|---|---|
| Cellular Location | Secreted. |
| Tissue Location | Expressed abundantly in the central nervous system of adult, but not at all in fetal brain. High levels of SCRG1 transcripts are also observed in testis and aorta |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus.
References
Hu,Y., Mol. Cell Proteomics 4 (12), 2000-2009 (2005)Clark,H.F., Genome Res. 13 (10), 2265-2270 (2003)Dron,M., J. Biol. Chem. 273 (29), 18015-18018 (1998)
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