|Other Names||WW domain-binding protein 2, WBP-2, WBP2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7786b was selected from the C-term region of human WBP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. WBP2 is a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined.
Dhananjayan,S.C., Mol. Endocrinol. 20 (10), 2343-2354 (2006)Nitsch,R., Biochem. J. 377 (PT 3), 553-560 (2004)Jolliffe,C.N., Biochem. J. 351 PT 3, 557-565 (2000)
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