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MAX Antibody (S11) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P61244
Clone Names 109144
Additional Information
Gene ID 4149
Other Names Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X, MAX, BHLHD4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7827a was selected from the S11 region of human MAX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAX
Synonyms BHLHD4
Function Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
Cellular Location Nucleus. Cell projection, dendrite
Tissue Location High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle
Research Areas
Citations (0)

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MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.


Faiola,F., Biochem. J. 403 (3), 397-407 (2007)Gordan,J.D., Cancer Cell 11 (4), 335-347 (2007)Fujii,M., Mol. Cell 24 (5), 771-783 (2006)

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$ 80.00
Cat# BP7827a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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