|Other Names||Aldehyde dehydrogenase X, mitochondrial, Aldehyde dehydrogenase 5, Aldehyde dehydrogenase family 1 member B1, ALDH1B1, ALDH5, ALDHX|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7851a was selected from the N-term region of human ALDH1B1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.|
|Cellular Location||Mitochondrion matrix.|
|Tissue Location||Liver, testis and to a lesser extent in brain.|
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Provided below are standard protocols that you may find useful for product applications.
ALDH1B1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.
Husemoen,L.L., Alcohol. Clin. Exp. Res. 32 (11), 1984-1991 (2008)Yokoyama,A., Int. J. Cancer 121 (5), 1047-1054 (2007)Stewart,M.J., Biochem. Biophys. Res. Commun. 211 (1), 144-151 (1995)
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